5-[bis-2(chloro-ethyl)-amino]-2,4-dinitro-benzamide

5-[bis-2(chloro-ethyl)-amino]-2,4-dinitro-benzamide is a synthetic small molecule belonging to the dinitroaniline class. It has been studied as an experimental compound and is not approved for clinical use. The compound features a bis(2-chloroethyl)amino group attached to a dinitrobenzamide core. Mechanistically, it has demonstrated inhibitory activity against bacterial nitroreductase enzymes in vitro (notably from Escherichia coli and Staphylococcus saprophyticus), with reported IC50 and Ki values in the micromolar range. There are no known approved indications or marketed formulations for this agent[1][3]. Its primary research interest appears to be as an enzyme inhibitor in biochemical assays.

Other names

5-(bis(2-chloroethyl)amino)-2,4-dinitrobenzamide